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The 11 runtime attacks breaking AI security — and how CISOs are stopping them


Enterprise security teams are losing ground to AI-enabled attacks — not because defenses are weak, but because the threat model has shifted. As AI agents move into production, attackers are exploiting runtime weaknesses where breakout times are measured in seconds, patch windows in hours, and traditional security has little visibility or control.

CrowdStrike's 2025 Global Threat Report documents breakout times as fast as 51 seconds. Attackers are moving from initial access to lateral movement before most security teams get their first alert. The same report found 79% of detections were malware-free, with adversaries using hands-on keyboard techniques that bypass traditional endpoint defenses entirely.

CISOs’ latest challenge is not getting reverse-engineered in 72 hours

Mike Riemer, field CISO at Ivanti, has watched AI collapse the window between patch release and weaponization.

"Threat actors are reverse engineering patches within 72 hours," Riemer told VentureBeat. "If a customer doesn't patch within 72 ...


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