EchoPrime – Cedars-Sinai’s AI system can read echocardiograms and write the report

EchoPrime, published in Nature in February 2026, outperforms both task-specific AI tools and previous foundation models across 23 cardiac benchmarks, and its code, weights, and a demo are publicly available.

An echocardiogram is one of the most common diagnostic tools in cardiology: an ultrasound of the heart that reveals how it moves, how its chambers fill and empty, and whether its structure is compromised. Interpreting one requires training, time, and a specific kind of spatial attention, the ability to look at moving images of a beating heart and translate them into a clinical narrative.

Researchers at Cedars-Sinai Medical Center, working with colleagues from Kaiser Permanente Northern California, Stanford Health Care, Beth Israel Deaconess Medical Center in Boston, and Chang Gung Memorial Hospital in Taiwan, have built an AI system that can do the same thing.

EchoPrime, a video-based vision-language model, analyses echocardiogram footage and generates a written report of cardiac ...